Naruto - Orochimaru

He was originally one of the Legendary Sannin of Kohona. He was once considered to be a Genius. But his ambitions drove him to leave konoha in search for eternal life, the mastery of all Jutsu known to man and total knowledge. He was caught experimenting on shinobi of the hidden leaf and had a square off vsing the 3rd hokage and Enma. But since the 3rd was naive he let the shinobi escape from the hidden leaf. A move that would come back to haunt him later on. After Orochimaru left Konoha he joined a Elite criminal organization called Akatsuki. His goal in akatsuki was to get close to Uchiha Itachi to get his body and eyes but Uchiha Itachi became too powerful for him so he set his eyes on the “young chick” Sasuke Uchiha, Uchiha Itachi’s younger brother. During the Chuunin exams he came  and gave Sasuke forcefully the curse seal mark knowing that Sasuke would come to him to recieve more power.  Him and the Hidden Village of the Sand who he was secretly controlling using the idea that the treaty they had with the leaf was making them weaker used it to convince them to crush Kohona.  During the Invasion him and his old master Sarutobi-sensei ( which was the 3rd hokage.) faced off in mortal combat. Orochimaru prepared a treat for the 3rd hokage. He used his forbidden Edo-Tensei jutsu to summon the 1st and 2nd Hokages using Sacrifices. the 3rd Hokage faced them in combat and beat them using the forbidden Shiki Fuujin sealing technique developed by the 4th hokage who was suppose to succeed him.  Sarutobi the 3rd Hokage managed  to rip the spirit life of Orochimarus. Because of the 3rd Hokages attempt to seal Orochimarus Jutsu ability he was forced to do a body transfer and wait 3 more years before he could get Sasuke Uchihas body. This bought Team kakashi time to try and save Sasuke.  Orochimarus Henchmen came after sasuke and gave him the Curse Seal 2 but Sasuke managed to escape but still ended up going to Orochimarus where Orochimaru trained him for 3 years getting his body ready for the soul transfer. After those 3 years were up Sasuke and Orochimaru had a final showdown and Sasuke killed him. That was Orochimarus trap because the soul transfer and take over can’t begain untill orochimaru is killed by the subordinate. But Sasukes willpower was so great in the soul transfer area that he took over and Orochimarus soul was trapped and supressed with Sasukes Chakra. Later on though Orochimaru made a return once sasuke ran out of chakra. Just as Orochimaru was going to take Sasuke Uchihas body he failed because he was stabbed by the Sword of Sasunoo and sealed.